Physiological functions of GABA

The physiological functions of GABA are mainly as following:

 (1) Calm down anxiety.  GABA can reduce the activity of neurons, activate anti-anxiety brain receptor, and prevent the anxiety information to reach the brain central nervous system. GABA can calm down nerves anxiety, relieve stress, and promote better sleep.

(2) Reduce blood pressure.  GABA can promote the expansion of blood vessels effectively, and reduce blood pressure by regulating the central nervous system. It is reported that GABA is the anti-hypertensive constituents in Astragalus and Chinese traditional Monascus product.

(3) Treat disease.  Some diseases related to the concentration of GABA in body of patients. Lower concentration of GABA in spinal cord was detected in patients with Parkinson's disease, and the concentration of GABA in patients with epilepsy is also lower than the normal level. The decrease of GABA probably causes the formation of Huntington disease, Alzheimer's and other neurological decline disease.

(4) Reduce blood ammonia.  GABA can inhibit glutamate decarboxylation, and make blood ammonia decrease. Glutamate can combine more ammonia in blood to form urea to excrete. So GABA can remove ammonia toxicity, and promote liver function.

(5) Improve brain activity.  GABA can enter the brain tricarboxylic acid cycle, promote brain cell metabolism, improve glucose metabolism of glucose phosphatase activity. It may increases acetylcholine production, dilates blood vessels and increase blood flow, and restores the brain cell function.

(6) Others.  GABA also has other functions, such as preventing skin aging, improving lipid metabolism, preventing arteriosclerosis.